Study 01
Niacinamide + Hyaluronic Acid
A 2024 controlled clinical trial of 44 women applying a 6% niacinamide and hyaluronic acid formula for two months found measurable improvements in fine lines, wrinkles, luminosity, smoothness, and skin plumpness. Genomic analysis confirmed changes in collagen and matrix-related gene expression.
Source: Scientific Reports (Nature Publishing), 2024 — peer-reviewed clinical study.
Found in: The House Boost · The House Soft
Study 02
Retinoids
Decades of clinical evidence position retinoids as the gold standard for anti-aging. Mechanistically, retinol stimulates fibroblasts (the cells that produce collagen and elastin), increases epidermal thickness, and accelerates cell turnover via TGF-β signaling pathways.
Source: International Journal of Cosmetic Science; Journal of Dermatological Treatment — multi-decade evidence base.
Found in: The House Bounce · The House Renewal
Study 03
Peptides + Vitamin C
A clinical study of a peptide and vitamin C formulation showed measurable wrinkle reduction after 28–29 days: crow's-feet decreased 9%, forehead wrinkles 11%, and 3D analysis showed an 11.5% overall reduction in wrinkles. 65–79% of subjects reported visible smoothing and brightness.
Source: International Journal of Cosmetic Science (Escobar et al., 2021).
Found in: The House Firm · The House Eye · The House Defense · The House Boost
Study 04
Hyaluronic Acid
Topical hyaluronic acid is clinically proven to increase skin hydration, restore epidermal thickness, and reduce p16 senescence markers in the dermis. Effects are most pronounced when multiple molecular weights are combined — exactly what's used across this line.
Source: Scientific Reports, 2024; multiple peer-reviewed studies on dermatoporosis patients.
Found in: The House Hyaluronic · The House Soft · The House Bounce · The House Eye
Study 05
Vitamin C (Ascorbic Acid)
Vitamin C is a cofactor required for collagen synthesis and a potent antioxidant. Stable derivatives like 3-O-ethyl ascorbic acid (used in The House Boost) and tetrahexyldecyl ascorbate (used in The House Defense) deliver the brightening and antioxidant benefits without the irritation of L-ascorbic acid.
Source: Antioxidants Journal (PubMed PMC9495646), 2022.
Found in: The House Boost · The House Defense
Study 06
Glycolic Acid (AHA)
Alpha hydroxy acids like glycolic acid are clinically proven to improve skin texture, reduce hyperpigmentation, and accelerate cell turnover. Effective at low concentrations when paired with hydrating actives — which is why The House Renewal pairs it with squalane, glycerin, and panthenol.
Source: Reviewed in Journal of the American Academy of Dermatology and dermatology textbooks.
Found in: The House Renewal
Research summarized above examines individual active ingredients and ingredient classes in published clinical studies. Daniel's House products contain these actives at cosmetic concentrations and are not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. For specific medical concerns, consult a dermatologist.